Synonyms

Arrhinencephaly

HPE

OrphaNet reference

Holoprosencephaly 

Is A

Forebrain hypoplasia

Subtypes

Alobar holoprosencephaly

Lobar holoprosencephaly

Semilobar holoprosencephaly

May Cause

Abnormal configuration of cerebral ventricles

Abnormal septum pellucidum

Ambiguous genitalia

Anophthalmia

Cebocephaly

Choanal atresia

Choanal stenosis

Cleft lip/palate

Coloboma

Congenital brain malformation

Congenital premature craniosynostosis

Facial hypoplasia

Hydrocephalus

Hydrops fetalis

Hypotelorism

Intracranial lesion in an infant

Malformed orbit

Microcephaly

Microphthalmia

Midline cystic mass in fetal brain

Neuronal migration disorder

Radial ray hypoplasia

Retinopathy

Single maxillary central incisor

Trigonocephaly

May Be Caused by

Agnathia - holoprosencephaly - situs inversus

Genoa syndrome

Holoprosencephaly - craniosynostosis

Holoprosencephaly - radial heart renal anomalies

Steinfeld syndrome