Synonyms

Primary hypertrophic osteoarthropathy

OrphaNet reference

Pachydermoperiostosis 

May Cause

Acro-osteolysis

Arterial occlusion

Arterial tortuosity

Broad tubular bones

Clubbing of digits

Congenital skull defect

Congenital widespread osteosclerosis

Congenitally limited joint mobility

Cortical bone thickening

Defective cranial ossification

Dense or thick skull

Diffusely dense skull base

Enthesopathy

Exostosis

Eyelid ptosis

Hyperhidrosis

Hypertrophic osteoarthropathy

Ichthyosis

Incomplete ossification of cranial sutures

Large fontanelle

Large hands for age

Limited joint mobility

Localized cortical bone thickening

Multiple expanding rib lesions

Osteosclerosis

Periosteal new bone formation in a child

Polyostotic bone lesions in children

Sclerosing bone dysplasia

Short and broad distal phalanges of hand

Soft-tissue calcification

Soft-tissue ossification

Thick heel pad

Thick periosteal reaction along bone shaft

Thick ribs

Wide sutures

Widespread cortical bone thickening

Widespread osteosclerosis

Widespread periosteal reaction

Widespread predominantly cortical osteosclerosis

Widespread soft-tissue calcification

Wormian bones

Wrinkled skin