Gamuts

Sclerosteosis

Sclerosteosis is an autosomal recessive disorder characterized by bone overgrowth. It was first described in 1958 but given the current name in 1967. [Source: Wikipedia ]

OrphaNet reference
Sclerosteosis 
May Cause
Calvarial hyperostosis
Cataract
Congenital macrocephaly
Congenital prognathism
Congenital widespread osteosclerosis
Cranial nerve paresis or paralysis
Craniotubular dysplasia
Deafness
Defective dentition
Delayed dentition
Dense or thick skull
Dental defect
Diffusely dense skull base
Exophthalmos
Frontal bossing
Gigantism
Hyperphosphatasemia
Hypertelorism
Macrocephaly
Nail aplasia
Nail deformity
Nail dystrophy
Nail hypoplasia
Optic atrophy
Osteosclerosis
Sclerosing bone dysplasia
Short middle phalanges
Syndactyly
Thick clavicle
Thick ribs
Thick tubular hand bones
Transverse dense metaphyseal bands
Widespread osteosclerosis of medullary and cortical bone
Widespread predominantly medullary osteosclerosis
Wormian bones

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