Hyperuricemia - anemia - renal failure

Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months to years. Initially there are generally no symptoms; later, symptoms may include leg swelling, feeling tired, vomiting, loss of appetite, and confusion. [Source: Wikipedia ]

Familial juvenile hyperuricemic nephropathy type 2
FJHN type 2
OrphaNet reference
Hyperuricemia - anemia - renal failure 
May Cause
Renal failure