Breck disease

An infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. [Source: Wikipedia ]

Osteonecrosis of the medial malleolus
Is A
Site-specific avascular necrosis