Lobulated tongue

Orofaciodigital syndrome 1 (OFD1), also called Papillon-League and Psaume syndrome, is an X-linked congenital disorder characterized by malformations of the face, oral cavity, and digits with polycystic kidney disease and variable involvement of the central nervous system. Cause Orofaciodigital syndrome type 1 is caused by mutations in the OFD1 gene. [Source: Wikipedia ]