Hypospadias is a common variation in fetal development of the penis in which the urethra does not open from its usual location in the head of the penis. It is the second-most common birth abnormality of the male reproductive system, affecting about one of every 250 males at birth. [Source: Wikipedia ]

May Cause
Bifid scrotum
Limb asymmetry
Wide pubic symphysis
May Be Caused by
Abruzzo-Erickson syndrome
Androgen insensitivity syndrome
Aniridia-Wilms tumor association
Autosomal recessive polycystic kidney disease
Bifid epiglottis
Branchiogenitoskeletal syndrome
CHARGE-like syndrome
Dubowitz syndrome
Familial hypertelorism
Familial hypospadias
Fanconi anemia
Fetal primidone syndrome
Fontaine-Farriaux syndrome
Fraser syndrome
Gardner-Silengo-Wachtel syndrome
Hadju-Cheney syndrome
Hand-foot-genital syndrome
Hypertelorism - hypospadias - polysyndactyly syndrome
Hypospadias - hypertelorism - coloboma and deafness
Hypospadias - intellectual deficit Goldblatt type
Lenz microphthalmia syndrome
LEOPARD syndrome
Lin-Gettig syndrome
Lower limb deficiency - hypospadias
Male pseudohermaphroditism
Mowat-Wilson syndrome
Myopathy - growth delay - intellectual deficit - hypospadias
N syndrome
Naguib-Richieri-Costa syndrome
Opitz BBBG syndrome
Osteoglophonic dysplasia
Pfeiffer-type dolichocephalosyndactyly
Potter sequence
Rapp-Hodgkin syndrome
Reifenstein syndrome
Rieger syndrome
Ritscher-Shinzel syndrome
Schilbach-Rott syndrome
Schinzel-Giedion syndrome
Silver-Russell syndrome
Smith-Lemli-Opitz syndrome
Spina bifida - hypospadias
Splenogonadal fusion-limb deformity syndrome
Spondylocostal dysostosis - hypospadias - intellectual deficit
Toriello-Carey syndrome
Tracheo-esophageal fistula - hypospadias
Tracheoesophageal fistula-gastrointestinal abnormality-hypospadias-growth deficiency
Trisomy 21
VATER association
Zellweger syndrome