May Cause

Diffusely enlarged uterus

Large hands for age

Premature epiphyseal fusion

May Be Caused by

Adrenal enzyme deficiency

Adrenal tumor

Chromosome 14 uniparental disomy syndrome

Chromosome 15q dup syndrome

Chromosome 9:del(9p) syndrome

Chromosome 9q dup syndrome

Cohen syndrome

Enchondromatosis

Epidermal nevus syndrome

Hypothyroidism

Idiopathic precocious puberty

Infection

Irradiation

Klinefelter syndrome

Myelomeningocele

Neurofibromatosis

Orofaciodigital syndrome

Pallister-Hall syndrome

Paraneoplastic syndrome

Polyostotic fibrous dysplasia

Proteus syndrome

Seckel syndrome

Shapiro syndrome

Spastic paraplegia - precocious puberty

Trauma

Tuberous sclerosis

Williams syndrome

X-linked intellectual deficit - precocious puberty - obesity

XXX syndrome