Acromegaly

Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. [Source: Wikipedia ]

Synonyms
Hypersomatotropism
OrphaNet reference
Acromegaly 
May Cause
Advanced mastoid pneumatization
Altered calcium concentration
Altered phosphorus concentration
Arterial dilatation
Arthritis
Arthropathy
Bilateral large kidneys
Bone-within-a-bone appearance
Cardiomyopathy
Carpal and/or tarsal fusion
Carpal fusion
Chondral calcification
Chondrocalcinosis
Clubbing of digits
Congenital narrow spinal canal
Cortical bone thickening
Degenerative joint changes
Diffusely dense calvarium
Disk calcification
Ear cartilage calcification
Enlarged gallbladder
Enlarged orbital rectus muscles
Enlarged vertebrae
Enthesopathy
External ear calcification
Extraocular muscle enlargement
Generalized osteopenia or osteolysis of the jaws
Generalized osteoporosis
Gigantism
Hyperphosphatemia
Hyperpituitarism
Hypertension
Increased pneumatization of mastoids
Increased soft-tissue interstitial markings
Intervertebral disk calcification
Intra-articular calcification
Kyphosis
Large hands for age
Large sella turcica
Long thin bones
Macroglossia
Narrow spinal canal
Periarticular calcification
Polyarticular joint disease
Posterior vertebral scalloping
Premature osteoarthritis
Secondary osteoarthritis of the hip
Spinal osteopenia
Thick heel pad
Thick ribs
Thick skull
Wide intervertebral disk space
Widened joint space
Widespread cortical bone thickening
Widespread demineralization with coarse trabeculation
Widespread periosteal reaction
May Be Caused by
X-linked intellectual deficit - acromegaly - hyperactivity
Hypersomatotropism