Non-neoplastic bone lesion

Giant-cell tumor of the bone (GCTOB), is a relatively uncommon tumor of the bone. It is characterized by the presence of multinucleated giant cells (osteoclast-like cells). [Source: Wikipedia ]

May Be Caused by

Common: Avascular necrosis; Bone cyst; Bone infarct; Bone island; Brown tumor of hyperparathyroidism; Cortical desmoid; Fibrous cortical defect; Fibrous dysplasia; Gouty tophus; Healing stress fracture; Langerhans cell histiocytosis; Osteochondrosis dissecans; Osteoid osteoma; Osteomyelitis; Paget disease of bone; Parosteal myositis ossificans; Periosteal desmoid; Subchondral cyst
Uncommon: Amyloidosis; Aneurysmal bone cyst; Dermoid; Epidermoid; Epidermoid inclusion cyst; Fibromatosis; Foreign body granuloma; Foreign body reaction; Giant cell granuloma; Giant cell tumor of tendon sheath; Glomus tumor; Hemophilic pseudotumor; Hydatid cyst; Intraosseous ganglion; Multicentric infantile myofibromatosis; Osteofibrous dysplasia; Pigmented villonodular synovitis; Plasma cell granuloma; Post-traumatic cyst; Posttraumatic osteolysis; Sarcoidosis; Sternocostoclavicular hyperostosis; Xanthomatous lesion