OrphaNet reference

Classical homocystinuria 

May Cause

Acute pancreatitis

Advanced bone age

Alopecia

Anisospondyly

Arachnodactyly

Arterial calcification

Arterial dilatation

Arterial occlusion

Atherosclerosis

Biconcave vertebra

Bowed bones

Bowed tubular bones

Cataract

Clubfoot

Congenital foot deformity

Congenital generalized osteoporosis

Congenital heart disease

Congenital hepatomegaly

Congenital vertebral abnormality

Defective dentition

Delayed dentition

Dense epiphyses of hands and feet

Dense or thick skull

Dental defect

Diffusely dense calvarium

Disk calcification

Generalized wide epiphyseal plate

Genu valgum

Gigantism

Glaucoma

Intervertebral disk calcification

Intracranial calcification

Irregular epiphyseal ossification centers

Irregular epiphysis

Kyphoscoliosis

Lens dislocation

Long thin bones

Macrophthalmia

Marfanoid appearance

Metatarsus adductus

Microcephaly

Microspherophakia

Multiple abnormal epiphyses

Multiple fractures

Multiple intracranial calcification

Myocardial infarction

Myopia

Optic atrophy

Osteoporosis

Pancreatitis in a child

Pathologic fracture

Pectus carinatum

Pectus excavatum

Pes planus

Platyspondyly

Protrusio acetabuli

Renal artery aneurysm or microaneurysm

Sclerotic epiphysis

Scoliosis

Skin pigment abnormality

Skin rash

Soft-tissue calcification

Spinal osteopenia

Thick skull

Thromboembolism

Vascular calcification

Venous thrombosis

Widespread soft-tissue calcification