Scleroderma

Synonyms
Progressive systemic sclerosis
Systemic sclerosis
OrphaNet reference
Scleroderma 
Is A
Connective tissue disease
Subtypes
Acrosclerosis
CREST syndrome
May Cause
Abdominal wall calcification
Achalasia
Acquired absence of phalanx, digit, hand, or foot
Acro-osteolysis
Acro-osteosclerosis
Air in esophagus
Arthritis
Arthritis with osteoporosis
Arthritis with swan-neck deformity
Arthropathy
Atlantoaxial instability
Avascular necrosis
Bilateral basilar lung disease
Bilateral small kidneys
Blind loop syndrome
Bone infarct
Calcification about the fingertips
Cardiomegaly
Cardiomyopathy
Carpal and/or tarsal fusion
Carpal fusion
Chondral calcification
Chronic Kerley lines
Chronic nonobstructive small bowel distention
Clubbing of digits
Colonic distention without obstruction
Decreased fold pattern in duodenum and small bowel
Decreased subcutaneous fat
Degenerative joint changes
Dense epiphyses of hands and feet
Dental defect
Dilated small bowel with normal mucosal folds
Distal clavicle defect
Distal tapering of short tubular bones of the hands and feet
Duodenal dilatation without obstruction
End-stage interstitial fibrosis
Enlarged orbital rectus muscles
Eosinophilia
Esophageal dysfunction
Esophageal dysmotility
Fingertip calcification
Functional pharyngeal disorder
Gangrene of finger or toe
Gastrointestinal dysfunction
Hyperechoic renal cortex
Interstitial lung fibrosis
Intestinal pseudo-obstruction
Intra-articular calcification
Limb reduction
Limited joint mobility
Loss of lamina dura of teeth
Lower lung disease
Lung abscess
Lytic skeletal lesion
Malabsorption
Malabsorption pattern in small bowel
Megacolon
Microcardia
Microstomia
Middle mediastinal lesion
Mucosal destruction of small bowel
Narrowed joint space
Neuropathic bone changes of the hands or feet
Non-obstructive gastric dilatation
Nonvisceral abdominal calcification
Notching of the superior rib margins
Osteolysis
Osteomalacia
Panniculitis
Periarticular calcification
Peribronchovascular interstitial thickening
Pericardial effusion
Pneumatosis intestinalis
Polyarticular joint disease
Pulmonary hypertension
Raynaud phenomenon
Recurrent pneumonia
Reflux esophagitis
Residual intestinal barium
Resorption of distal clavicle
Retained material in hypopharynx
Rheumatoid-like arthritis
Ribbon-like ribs
Rickets
Salivary gland enlargement
Sclerotic foot bone lesion
Sclerotic hand bone lesion
Skin aplasia
Skin atrophy
Skin calcification
Skin hypoplasia
Small bowel pseudodiverticulum
Soft-tissue calcification
Superior mesenteric artery syndrome
Thin ribs
Transverse mucosal folds in the esophagus
Wavy ribs
Widespread abdominal calcifications
Widespread irregular esophageal mucosa
Widespread small irregular lung opacities
Widespread soft-tissue calcification

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