Gamuts

Dyskeratosis congenita

Dyskeratosis congenita (DKC),also known as Zinsser-Engman-Cole syndrome, is a rare progressive congenital disorder with a highly variable phenotype. The entity was classically defined by the triad of abnormal skin pigmentation, nail dystrophy, and leukoplakia of the oral mucosa, but these components do not always occur. [Source: Wikipedia ]

Synonyms
DKC
Dyskeratosis congenita syndrome
Zinsser-Engman-Cole syndrome
OrphaNet reference
Dyskeratosis congenita 
May Cause
Acquired esophageal stenosis
Alopecia
Anemia
Anorectal anomaly
Deafness
Defective dentition
Delayed dentition
Dental caries
Hyperhidrosis
Hyperkeratosis
Immune disorder
Increased risk of neoplasm
Intracranial calcification
Microorchidism
Nail aplasia
Nail deformity
Nail dystrophy
Nail hypoplasia
Pancytopenia
Pathologic fracture
Skin pigment abnormality
Telangiectasia
Thrombocytopenia
Tongue abnormality
Vaginal atresia
Synonyms
DKC
Dyskeratosis congenita syndrome
Zinsser-Engman-Cole syndrome
OrphaNet reference
Dyskeratosis congenita 
May Cause
Acquired esophageal stenosis
Alopecia
Anemia
Anorectal anomaly
Deafness
Defective dentition
Delayed dentition
Dental caries
Hyperhidrosis
Hyperkeratosis
Immune disorder
Increased risk of neoplasm
Intracranial calcification
Microorchidism
Nail aplasia
Nail deformity
Nail dystrophy
Nail hypoplasia
Pancytopenia
Pathologic fracture
Skin pigment abnormality
Telangiectasia
Thrombocytopenia
Tongue abnormality
Vaginal atresia


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