Trisomy 18

Edwards syndrome, also known as trisomy 18, is a genetic disorder caused by the presence of a third copy of all or part of chromosome 18. Many parts of the body are affected. [Source: Wikipedia ]

Edwards syndrome
OrphaNet reference
Trisomy 18 
Is A
Trisomy syndrome
May Cause
Abnormal eyelashes
Abnormal sternum
Absent clavicle
Absent digit
Absent nose
Absent thumb
Agenesis or hypoplasia of the corpus callosum
Ankyloblepharon filiforme adnatum
Blue sclerae
Choanal atresia
Choanal stenosis
Clavicle hypoplasia
Clinodactyly of fifth finger
Coarctation of aorta
Common origin of carotid arteries
Congenital abnormality of great toe
Congenital foot deformity
Congenital generalized osteoporosis
Congenital heart disease
Congenital intestinal malrotation
Congenital midface hypoplasia
Congenital premature craniosynostosis
Congenital renal cystic disease
Congenital renal or ureteral anomaly
Congenital short hands and feet
Congenital skull defect
Congenital vertebral abnormality
Congenitally abnormal pelvis
Congenitally limited joint mobility
Contracted hand
Decreased number of ribs
Defective cranial ossification
Delayed closure of fontanelles
Diaphragmatic hernia
Eleven pairs of ribs
Elongated clavicle
Esophageal atresia
External ear malformation
Eyebrow anomaly
Facial hypoplasia
Generalized skull thinning
Genital anomaly
Handlebar clavicle
Humerus-radius-ulna synostosis
Hydrops fetalis
Hypoplastic pelvis
Hypoplastic terminal phalanges
Hypoplastic thumb
Hypospadias or ambiguous external genitalia
Incomplete ossification of cranial sutures
Increased nuchal fold
Inner ear anomaly
Intestinal malrotation
Irregular epiphyseal ossification centers
Large fontanelle
Limited joint mobility
Long thin bones
Macular stains
Middle ear anomaly
Multiple abnormal epiphyses
Multiple sclerotic foci in an infant or child
Nail aplasia
Nail deformity
Nail dystrophy
Nail hypoplasia
Nephrogenic rests
Nuchal cystic hygroma
Patent ductus arteriosus
Prominent occiput
Pulmonic stenosis
Radial ray hypoplasia
Radial ray syndrome
Radioulnar synostosis
Retarded skeletal maturation
Ribbon-like ribs
Short first metacarpal
Short first metatarsal
Short metacarpal
Short metatarsal
Short proximal phalanx
Short thin distal phalanx of thumb
Short thumb
Slender clavicle
Small nose
Small thymus in an infant
Stippled epiphyses
Synostosis of tubular bones
Thin and small distal phalanges of the hand
Thin clavicle
Thin ribs
Tracheoesophageal fistula
Type B pelvis
Undersegmentation of sternum
Uterine anomaly
Vaginal anomaly
Ventricular septal defect
Vertebral malsegmentation
Wavy ribs
Wide sutures
Wilms tumor