Sickle cell disease

Synonyms
SCD
Sickle cell anemia
Subtypes
Early sickle cell disease
May Cause
Abnormal sternum
Absent paranasal sinus
Acquired short hands and feet
Anemia
Arthritis
Arthropathy
Avascular necrosis
Biconcave vertebra
Bilateral large kidneys
Bone infarct
Bone-within-a-bone appearance
Broad tubular bones
Budd-Chiari syndrome
Cardiomegaly
Cardiomegaly in childhood
Cerebral thrombosis
Cerebral vasculitis
Cone-shaped epiphysis
Congenital generalized osteoporosis
Congenital hemolytic anemia
Congenital hepatomegaly
Congenital splenomegaly
Cortical bone thickening
Craniosynostosis
Dactylitis
Delayed bone age
Densely sclerotic vertebra
Diffusely dense calvarium
Diffusely dense spleen
Disk calcification
Dural sinus thrombosis
Encephalopathy
Endplate infarction
Epiphyseal necrosis
Erlenmeyer flask deformity
Flat femoral head
Focally dense calvarium
Fragmented femoral head
Fragmented or irregular femoral head
Frontal bossing
Gallstone
Generalized osteopenia or osteolysis of the jaws
Generalized osteoporosis
Hair-on-end skull
Heart failure
Heart failure in childhood
Hemolysis
Hepatosplenomegaly in a neonate
High-attenuation bile
High-output heart function
Humeral head deformity
Hyperechoic renal parenchyma
Hypoplastic paranasal sinus
Ischemia of digits
Joint effusion
Large anterior canal of a vertebral body
Localized brachydactyly
Localized bulge of the calvarium or scalp
Localized cortical bone thickening
Localized periosteal reaction
Loss of inner cortical bone margin
Loss of lamina dura of teeth
Lucent defect in bones of hands, wrists, feet, or ankles
Lung abscess
Lytic skeletal lesion
Mandibular periostitis
Medullary nephrocalcinosis
Metaphyseal cupping
Multiple collapsed vertebrae
Multiple expanding rib lesions
Multiple sclerotic foci in an infant or child
Multiple splenic calcifications
Nephropathy
Osteosclerosis
Perinephric hematoma
Periosteal new bone formation in a child
Periventricular T2 hyperintense lesion
Platyspondyly
Polyostotic bone lesions in children
Premature craniosynostosis
Primary anemia
Protrusio acetabuli
Pseudomacrodactyly
Pulmonary arterial hypertension
Pulmonary embolism
Pulmonary hypertension
Pulmonary venous hypertension
Raynaud phenomenon
Recurrent pneumonia
Renal cortical necrosis
Renal papillary necrosis
Renal vein thrombosis
Retinopathy
Rib lesion in a child
Sclerotic foot bone lesion
Sclerotic hand bone lesion
Short proximal phalanx
Shortened bone with premature growth-plate closure
Small kidney
Small or nonvisualized spleen
Solitary lesion of spleen
Spiculated periosteal reaction
Spinal osteopenia
Splenic calcification
Splenic infarction
Splenomegaly
Split cortex
Thick ribs
Thick skull
Thick tubular hand bones
Tibiotalar tilt
Transverse dense metaphyseal bands
Unilateral exophthalmos
Wide diametaphysis
Wide intervertebral disk space
Wide metaphysis
Widespread demineralization with coarse trabeculation
Widespread osteosclerosis
May Be Caused by
HbSS disease
Hereditary persistence of fetal hemoglobin - sickle cell disease
Sickle cell - beta-thalassemia disease
Sickle cell - hemoglobin C disease
Sickle cell - hemoglobin D disease
Sickle cell - hemoglobin E disease

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