Hemoglobin C disease

Hemoglobin c (abbreviated as HbC) is an abnormal hemoglobin in which glutamic acid residue at the 6th position of the β-globin chain is replaced with a lysine residue due to a point mutation in the HBB gene. It produces sickle cell trait but not the disease, as it causes only mild sickling of the RBCs. [Source: Wikipedia ]