Collaborative Hypertext of Radiology

Pelizaeus-Merzbacher syndrome

diffuse, symmetrical demyelination
- cerebrum
- cerebellum
- brainstem
- spinal cord
"islands" of partially demyelinated fibers
CT may be normal
two types:
- X-linked recessive (presents in infancy)
- autosomal dominant (preadulthood)

Charles E. Kahn, Jr., MD - 13 February 1995
Last updated: 1 October 2013